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AUSTRAL Biologicals Catalog

Product Sheet: Rabbit anti-Human p53-associated Parkin-like Cytoplasmic Protein (PARC) IgG fraction polyclonal antibody

Catalog NumberPCA-3000a-9
Product IdPCA-3000a-9
Product NameRabbit anti-Human p53-associated Parkin-like Cytoplasmic Protein (PARC) IgG fraction polyclonal antibody
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryPolyclonal Antibodies (Cancer/Apoptosis)
DescriptionIgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (FFFGDEEEDEDEAYD) corresponding to amino acids 2503-2517 of human PARC. The IgG fraction was purified using Protein G-Sepharose.
Mol WeightN/A
StorageStore at -20ºC.
StabilityStable at least one year at -20ºC. Avoid repeated freezing and thawing.
Biological ActivityThis polyclonal antibody reacts in ELISA (1: 250 dilution) and Western blot (1: 1,000 dilution) using the immunizing peptide. P53-associated parkin-like cytoplasmic protein (PARC) is a 270 kDa protein that acts as a cytoplasmic anchor for p53 unstressed cells, thereby regulating the localization and subsequent function of p53. It contains a cullin domain and a RING-IBR-RING domain at the carboxy terminus and it is ubiquitously expressed.
FormulationSolution at 0.5 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
ReferencesNikolaev, A.Y. et al. (2003) Cell 112, 29-40. Nikolaev, A.Y. & Gu, W. (2003) Cell Cycle 2, 169-171.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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