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AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Lymphocyte Function Associated Antigen 3 (LFA-3); CD58 IgG fraction (monoclonal)

Catalog NumberMA-CD58-6
Product IdMA-CD58-6
Product NameAnti-human Lymphocyte Function Associated Antigen 3 (LFA-3); CD58 IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Immunology Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 2B2/D3) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing
Biological ActivityThis antibody can be used in immunoprecipitation, and flow cytometry, it also inhibits the cytolytic T lymphocyte (CTL) activity. It recognizes CD58 (also known as LFA-3), a 60-70 kDa membrane glycoprotein member of the immunoglobulin super family. CD58 is expressed on haemopoetic cells and it functions as an adhesion molecule mediating a co-stimulatory signal through CD2.
FormulationSolution at 1.0 mg/mL in PBS
Referencesvan der Merwe, P.A. & Davis, S.J. (2003) Annu. Rev. Immunol. 21, 659 – 684; Wang, J-H. et. al. (1999) Cell 97, 791 – 803; Wallner, B.P. et. al. (1987) J. Exp. Med. 166, 923 – 932.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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