AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Lymphocyte Function Associated antigen 2 (LFA-2); CD2; (E-Rosette Receptor) IgG fraction (monoclonal)

Catalog NumberMA-CD2-6
Product IdMA-CD2-6
Product NameAnti-human Lymphocyte Function Associated antigen 2 (LFA-2); CD2; (E-Rosette Receptor) IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Immunology Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 8A2/H11) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing
Biological ActivityThis antibody can be used in immunoprecipitation, and flow cytometry. It also inhibits the cytolic T lymphocyte (CTL) activity. It recognizes CD2 (also known as LFA-2, or E-rosette receptor), a 50 kDa transmembrane glycoprotein expressed on T cells, NK cells, cortical thymocytes and most malignant cells of T cell origin. It binds CD58 (LFA-3) to mediate cell adhesion and it is also receptor for CD59, and CD48. CD2 plays a critical role in activation of T cells.
FormulationSolution at 0.5 mg/mL in PBS
Referencesvan der Merwe, P. A. & Davis S.J. (2003) Annu. Rev. Immunol. 21, 659 – 684 ; Hahn, W. et. al. (1992) Science, 256, 1805 – 1807 ; Moingeon, P. et. al. (1989) Immunol. Rev. 111, 111 – 144.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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