AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Complement Receptor 1 (CR1 or CD35) IgG fraction (monoclonal)

Catalog NumberMA-CD35-6
Product IdMA-CD35-6
Product NameAnti-human Complement Receptor 1 (CR1 or CD35) IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Immunology Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 5H3/B1) obtained by immunization of mice with a human B cell line. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing
Biological ActivityThis antibody can be used in ELISA assays. It recognizes human CD35 (CD21), a polymorphic protein expressed as four allelic variants with molecular weight of 160, 190, 220 and 250 kDa. CD35 is expressed on all peripheral blood cells with the exception of platelets, natural killer cells and most T cells. It binds immune complexes opsonized with the activated complement components C3b and C4b, leading to their clearance in the liver and spleen.
FormulationSolution at 1.0 mg/mL in PBS
ReferencesKrych-Golberg, M. & Atkinson, J.P. (2001) Immunol. Rev. 180, 112 – 122 ; Chen, Z. et. al. (2000) Immunol. Rev. 176, 194 – 204.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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