AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Class II Transactivator (Ciita) IgG fraction (monoclonal)

Catalog NumberMA-4031-5
Product IdMA-4031-5
Product NameAnti-human Class II Transactivator (Ciita) IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Immunology Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 7D3/A1) obtained by immunization of mice with recombinant human CIITA fusion protein. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing
Biological ActivityThis antibody can be used in ELISA, Western Blot, and immunoprecipitation. It recognizes CIITA, a non-DNA binding coactivator considered as the master regulator of basal and induced MHC class II specific gene expression. CIITA ensures a tight transcriptional control of these antigen-presenting genes to meet with local requirements for an adequate immune response.
FormulationSolution at 1.0 mg/mL in PBS
ReferencesLeibundGut-Landmann, S. et. al. (2004) Eur. J. Immunol. 34, 1513 – 1525; Van den Elsen, P. et. al. (2004) Curr. Opin. Immunol. 16, 67 – 75 ; Naves, R. et. al. (2002) Int. Immunol. 14, 481 – 491.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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