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AUSTRAL Biologicals Catalog

Product Sheet: Anti-human CD3 IgG fraction (monoclonal)

Catalog NumberMA-CD3-6
Product IdMA-CD3-6
Product NameAnti-human CD3 IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Immunology Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 3C3/D4) obtained by immunization of mice with human peripheral T cells. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing
Biological ActivityThis antibody can be used in flow citometry studies. It recognizes human CD3. The CD3 antigen is expressed by peripheral T cells, thymocytes, and activated natural killer cells, and is also present in the great majority of T-cell neoplasms. CD3 complex consists of five different polypeptides chains and it is involved in signal transduction to the T cell interior following antigen recognition by the T cell receptor.
FormulationSolution at 0.5 mg/mL in PBS
ReferencesAlarcón, B. et. al. (2003) Immunol. Rev. 191, 38 – 46 ; Werlen, G. et. al. (2003) Science 299, 1859 – 1863 ; Kung, P.C. et. al. (1979) Science 206, 347 - 349.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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