AUSTRAL Biologicals Catalog

Product Sheet: Anti-human CD45 (Leukocyte Common Antigen) IgG fraction (monoclonal)

Catalog NumberMA-CD45-6
Product IdMA-CD45-6
Product NameAnti-human CD45 (Leukocyte Common Antigen) IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Immunology Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 8G3/A1) obtained by immunization of mice with human lymphocytes. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing
Biological ActivityThis antibody can be used in flow cytometry studies. It recognizes all isoforms of the CD45 (LCA). CD45 is a transmembrane tyrosine phosphatase, expressed on nucleated hematopoitic cells, which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing. CD45 functions as a leukocyte membrane receptor signal transduction. It plays an essential role in the regulation of leukocyte activation, development, and function.
FormulationSolution at 1.0 mg/mL in PBS
ReferencesMustelin, T. et al. (2004) Mol. Immunol. 41, 687 – 700 ; Trowbridge, I.S. et. al. (1994) Annu. Rev. Immunol. 12, 85 – 116 ; Justement, L.B. et. al. (1991) Science 252, 1839 – 1842.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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