AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Vascular Endothelial Growth Factor receptor 1 (VEGFR-1 or FLT-1) IgG fraction (monoclonal)

Catalog NumberMR-851-7
Product IdMR-851-7
Product NameAnti-human Vascular Endothelial Growth Factor receptor 1 (VEGFR-1 or FLT-1) IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Growth Factors/Cytokines/Receptors)
DescriptionIgG fraction from mouse monoclonal antibody (clone 6D1/G11) obtained by immunization of mice with the extracellular domain of human VEGFR-1 (106 kDa). The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing
Biological ActivityThis antibody can be used in ELISA assays (1: 8,000 dilution). It recognizes the extracellular domain of human VEGFR-1, a type I membrane protein. This protein binds VEGF, PLGF and VEGFB and belongs to the tyrosine protein kinase family. The VEGFR-1 has a signaling role in mediating monocyte chemotaxis in tumor disease and performs an inhibitory role by sequestering VEGF and preventing its interaction with VEGFR-2
FormulationSolution at 1.0 mg/mL in PBS
ReferencesFerrara, N. et. al. (2003) Nat. Med. 9, 669 – 676; Cross, M.J. et. al. (2003) Trends Biochem. Sci. 28, 488 – 494.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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