AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Elongator Protein 1 (ELP1) IgG fraction (monoclonal)

Catalog NumberTM-1701Y-55
Product IdTM-1701Y-55
Product NameAnti-human Elongator Protein 1 (ELP1) IgG fraction (monoclonal)
CategoryProteins and Antibodies for Transcription Research
SubcategoryProteins and Antibodies
DescriptionIgG fraction from mouse monoclonal antibody (clone 7E8/G10) obtained by immunization of mice with the largest subunit of Elongator complex (130 kDa). The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing
Biological ActivityThis antibody can be used in ELISA assays (1: 1,000 dilution). It recognizes ELP1, the largest subunit of Elongator complex. Its function is not clear, but it has been demonstrated that the human Elongator facilitates transcription by RNA polymerase II in a chromatin- and acetyl-CoA-dependent manner.
FormulationSolution at 1.0 mg/mL in PBS
ReferencesKim, J-H. (2002) Proc. Natl. Acad. Sci. USA 99, 1241 – 1246; Hawkes, N. et al. (2002) J. Biol. Chem. 277, 3047 – 3052.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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