AUSTRAL Biologicals Catalog

Product Sheet: Interleukin-6 human (IL-6) (RECOMBINANT)

Catalog NumberCI-460-33
Product IdCI-460-33
Product NameInterleukin-6 human (IL-6) (RECOMBINANT)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryGrowth Factors/Cytokines/Enzymes
DescriptionHuman Interleukin-6 (IL-6) plays a role in the mediation of the inflammatory and immune response initiated by infection or injury. IL-6 acts on B cells by stimulating differentiation and antibody secretion. IL-6 also exhibits growth factor activity for mature thymic or peripheral T cells, and enhances the differentiation of cytotoxic T cells in the presence of IL-2 or IFNt. This glycoprotein is composed of 184 amino acid residues, and has a 42% homology with murine IL-6. Human Interleukin-6 (RECOMBINANT) is produced in genetically engineered Spodoptera frugiperda insect cells (Sf9) infected with recombinant viruses, and purified by sequential chromatography.
Mol Weight20-21 KDa (glycoprotein)
PurityOver 85% pure by SDS gel electrophoresis. There is < 1ng/mg endotoxin.
StorageStore at -80°C.
StabilityAt least 1 year at -80°C.
Biological Activity3H-thymidine uptake by B9 murine thymoma cell line that is IL-6 dependent.
FormulationFrozen liquid solution (PBS) at 0.50 mg/ml (50 µl/vial)
References1. Taga, T., and Kishimoto, T., (1997) Ann. Rev. Immunology, 15, 797-819
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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